Cerefolin Brain Wellness® Good for you and your brain

Cerefolin Brain Wellness® Good for you and your brain

 (1842 Reviews)

An MRI study showed that longer-term use was associated with significantly slower cognitive decline compared with matched untreated controls without elevated homocysteine levels.*

$60.99
$60.99 $69.99
SAVE 12% Sold out

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Cerefolin Brain Wellness® Good for you and your brain

Cerefolin Brain Wellness® Good for you and your brain

$60.99
$60.99 $69.99
SAVE 12% Sold out
  • local_shipping Free delivery for two piece or more

You deserve a mind as sharp and vital as you feel! Cerefolin Brain Wellness® is targeted nutrition for Mild Cognitive Impairment (MCI) with elevated homocysteine blood levels. It has been clinically proven* to reduce brain shrinkage1 as you age, compared to people not taking it. Starting early with Cerefolin Brain Wellness­® can help protect your brain cells, improve brain health, improve memory and focus, slow the loss of brain function, and improve your overall quality of life.1-4*

Neurologist recommended** and formerly only sold by prescription*, Cerefolin Brain Wellness® caplets provide specific nutrients you can’t get through diet alone to safeguard memory and cognitive function while actively combating the early signs of MCI.

Available to buy directly in 30 and 60 count packages. Available by prescription in a 90 count package.

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Use under medical supervision. †† Take one caplet daily either with or without food. Do not exceed the recommended dosage.

Consult your healthcare provider before use if you are pregnant, nursing, taking medication, or have any medical condition.

Cerefolin Brain Wellness® targeted nutrition is best when used long-term. Some users begin seeing results after 45 days of use, but results and timing of results vary.*

Functional Ingredients

  • 6 mg L-Methylfolate Calcium – This active form of folate supports memory- and focus-related neurotransmitter production, while improving brain metabolism.
  • 2 mg Vitamin B12 (Methylcobalamin) – This vitamin boosts energy production to support overall brain function.
  • 600 mg N-Acetyl-l-cysteine (NAC) – This antioxidant contributes to brain health by reducing oxidative stress.

Together these ingredients efficiently decrease homocysteine levels, which can help limit blood vessel damage and brain shrinkage linked to cognitive decline.

Ingredients

N-Acetyl-l-cysteine (NAC), Microcrystalline Cellulose and Silicon Dioxide, Hypromellose, L-Methylfolate Calcium, Magnesium Stearate (NF, Vegetable Source), Methylcobalamin.

Manufactured in the USA with high-quality ingredients sourced both from the U.S. and globally.

Keep out of reach of children.

Store in a cool, dry place at a controlled room temperature of 59°F to 86°F (15°C to 30°C). Protect from heat, light, and moisture.

 Frequently Asked Questions 

Cerefolin Brain Wellness® began as a targeted nutrition product prescribed by neurologists and is recommended by neurologists to address the early signs of mild cognitive decline, protecting memory and cognitive function*. The ingredients in Cerefolin Brain Wellness® are different from the ingredients found in most folic acid products.  Its formula provides the body with already-active folate (which means it can be absorbed and immediately used by the body because it doesn’t need to be broken down or activated), N-Acetyl-l-cysteine, and B12 that the body needs to address symptoms of Mild Cognitive Impairment (MCI). Most folic acid products need to be broken down in the body before the folate can be used, and many people may not be able to fully complete this activation.

Cerefolin Brain Wellness® is different from supplements. It is a clinically studied medical food, specifically formulated for the clinical dietary management of Mild Cognitive Impairment (MCI) associated with elevated homocysteine levels.

Its price reflects the science, quality, and care involved in its development and manufacturing, including:

  • Clinical research supporting the formulation, including studies in cognitive health and related biomarkers
  • Manufacturing in GMP-certified facilities that follow strict quality and safety standards, with every batch undergoing rigorous testing to help ensure consistency, purity, and compliance
  • Bioactive nutrients that the body can utilize directly, without additional conversion
  • Medical food regulatory standards, which require a product to meet a well substantiated distinctive nutritional requirement related to a disease or condition and not general wellness benefits as with dietary supplements

Cerefolin Brain Wellness® is priced to reflect its role as a targeted, science-based, specially formulated nutritional formula designed to meet the specific nutrient needs related to MCI for use under the guidance of a healthcare provider.

CerefolinNAC® has been replaced by Cerefolin Brain Wellness®. If you are searching for CerefolinNAC® or whether it is discontinued, it has been renamed and updated to Cerefolin Brain Wellness®. It contains the same medical food ingredients, now free from major allergens (milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, sesame, and soy), as well as dyes and colorants. The name was changed to better reflect improved accessibility for both patients and healthcare providers.

Healthcare providers look at a range of nutritional and health factors when evaluating people with mild to moderate cognitive impairment, including factors related to oxidative stress, homocysteine, L-methylfolate, and vitamin B12. Please consult your healthcare provider to see if Cerefolin Brain Wellness® is right for you.

Brain Results You Can't Ignore 

11.2x Slower Brain Shrinkage

A clinical study showed patients taking Cerefolin Brain Wellness® had up to 11.2 times slower rate of brain shrinkage than those not taking it. 1*

Better Cognitive Outcomes Over Time

An MRI study showed long-term use (over 2+ years) was associated with significantly better cognitive outcomes. 1*

Continued Use After 90 Days

After using the product for 90 days, 94% of users said once they tried it, they planned to continue.4*

 Cerefolin Brain Wellness® Is 

  • Major Allergen Free*

  • Caffeine Free

  • Dye Free

  • Gluten Free

  • Non-GMO

  • Preservative Free

  • Sodium Free

  • Sugar Free

  • Titanium Dioxide Free

     Disclaimers 

    Cerefolin Brain Wellness® is a medical food for the clinical dietary management of mild cognitive impairment with hyperhomocysteinemia and is specially formulated to meet the distinctive nutritional requirements for this condition. Use under medical supervision.

    **Based on prescriptions written by neurologists as a proxy for recommendation. In a 2025 survey conducted by Zappi, 93% of consumers surveyed indicated a doctor prescribing a product is a recommendation.

    § Images don’t portray actual consumers and are for illustration purposes only.

    || Testimonials based on experience with CerefolinNAC®*.

    * Cerefolin Brain Wellness®, formerly known and studied as CerefolinNAC®, is the same trusted and effective product that is now free from major allergens (milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, sesame and soy), dyes, and colorants.

    † By submitting this information, I hereby give Alfasigma USA, Inc. authorization to release, reproduce, use or distribute information about me, in original or modified form, for promotional and educational purposes in all forms of media, including print, broadcast or Internet. This information may include my medical information if I choose to submit any. I understand my information may be shared with a third party working on Alfasigma USA, Inc.’s behalf for promotional or educational purposes. I also understand that I may be contacted by this third party or Alfasigma USA, Inc. for more information.

    †† This product should be taken under medical supervision, and you should consult your healthcare provider before taking this for mild cognitive impairment.

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